• Health & Medicine
  • January 15, 2026

Swollen Lymph Nodes in Dogs: Causes, Diagnosis & Treatment Guide

So you found a lump on your dog's neck or behind their knee? My neighbor called me last week panicking about exactly that. Turns out it was swollen lymph nodes. Honestly, it scared the heck out of her until we figured things out. Let's cut through the confusion.

Those lumps? They're part of your dog's immune system. When lymph nodes swell up, it's like your dog's body waving a red flag. Could be minor, could be serious. Finding swollen lymph nodes in dogs isn't uncommon, but man, it always sends owners scrambling for answers.

Where to Find Dog Lymph Nodes (And How They Feel)

You know what surprised me? How many owners don't even know where to check. After my golden retriever Max had a scare last year, I made it my mission to learn all the spots:

Location What to Feel For Ease of Detection
Under jaw (submandibular) Firm pea-sized lumps beneath jaw angle ★★★★★ (Very easy)
Shoulder area (prescapular) Almond-shaped nodes in front of shoulders ★★★★☆ (Easy)
Armpit (axillary) Small movable lumps in armpit area ★★★☆☆ (Moderate)
Groin (inguinal) Soft lumps near hind leg crease ★★★☆☆ (Moderate)
Behind knee (popliteal) Pea-sized bump when leg is extended ★★★☆☆ (Moderate)

Normal lymph nodes? Think pea-sized and movable. When there's swelling of lymph nodes in dogs, they get bigger than a grape and feel firm. If you find one, don't freak out yet – but do call your vet.

Why Do Dog Lymph Nodes Swell Up?

I asked three vets this same question. Their answers boiled down to these main culprits:

The Common Stuff (Usually Fixable)

  • Local infections: Abscessed tooth making jaw nodes swell? Seen that!
  • Tick diseases: Lyme disease made my friend's lab have baseball-sized nodes
  • Fungal infections: Valley fever in southwestern states
  • Allergies: Environmental allergies cause mild swelling sometimes

Pro Tip: Swollen lymph nodes from infections usually feel warm and painful when touched. Your dog might resist you touching them.

The Serious Stuff (Needs Immediate Attention)

  • Lymphoma: This cancer causes multiple large, firm nodes
  • Metastatic cancer: When cancer spreads from elsewhere
  • Immune disorders: Like lupus (rare but happens)

Red Flags: If nodes are rock-hard, rapidly growing, or in multiple locations? Don't wait. That swelling of lymph nodes in dogs needs vet attention ASAP.

What Actually Happens At The Vet Visit

Here's exactly what to expect when you bring your dog in for swollen lymph nodes:

Step Procedure What It Reveals Cost Estimate
Physical Exam Palpating all lymph node locations Size, texture, pain response $50-$80
Needle Aspirate Withdrawing cells with small needle Cancer vs infection clues $120-$250
Biopsy Surgical removal of entire node Definitive cancer diagnosis $400-$900
Blood Tests Complete blood count + chemistry panel Infection markers, organ function $150-$300
Imaging X-rays/ultrasound of chest & abdomen Cancer spread assessment $300-$600

I'll be real with you – that biopsy cost stung when Max needed it. But knowing it wasn't cancer? Worth every penny.

Treatment Options For Swollen Dog Lymph Nodes

What happens next totally depends on the cause. Let me break down what my vet explained:

For Infections

  • Antibiotics: Like doxycycline ($25-$60 for 2-week course)
  • Antifungals: Itraconazole for valley fever ($120+/month)
  • Pain management: Carprofen if nodes are tender ($1-$2/day)

Most infections show improvement within 3-5 days. If not? Back to the vet.

For Lymphoma (Cancer)

This hits hard. Treatment choices depend on your budget and dog's age:

Treatment Type What It Involves Average Survival Time Cost Estimate
Chemotherapy Weekly IV treatments for 4-6 months 12-18 months $3,000-$7,000
Steroids Only Daily prednisone tablets 2-3 months $30-$80/month
Radiation Targeted radiation sessions Varies widely $5,000-$10,000

Honestly? The chemo cost shocked me. Some clinics offer payment plans though. Ask!

Home Care Strategies That Actually Help

Whether your dog's on meds or recovering, these practical tips help:

  • Warm Compresses: 10 minutes 3x/day for infected nodes
  • Pill Tricks: Hide meds in cream cheese or liverwurst
  • Monitor Size: Use a soft tape measure weekly
  • Appetite Watch: Cancer meds often cause nausea

I kept a symptom journal during Max's treatment. Vets loved having specific dates and measurements.

Unexpected Tip: Baby socks work great on dogs who scratch at neck nodes! Just watch they don't chew them.

Can You Prevent Lymph Node Swelling?

Totally fair question. While you can't prevent everything, these reduce risks:

  • Dental Care: Brush teeth weekly (prevents tooth root infections)
  • Tick Prevention: Use NexGard or Simparica monthly ($20-$25/month)
  • Cancer Screening: Senior dogs need bi-annual exams
  • Vaccinations: Keep distemper/parvo shots current

Is it foolproof? Nah. But it stacks the odds in your favor.

Your Burning Questions Answered (FAQ)

How long do swollen lymph nodes last in dogs?

Infection-related swelling usually improves within 1-2 weeks of treatment. Cancerous enlargement keeps progressing without intervention. If swelling persists beyond 14 days with antibiotics? Time for more tests.

Can allergies cause swollen lymph nodes in dogs?

Mildly, yes. But I've seen too many owners blame allergies when it was serious. If nodes are marble-sized or larger? Don't assume it's allergies. Get it checked.

Are swollen lymph nodes painful for dogs?

Infectious nodes often hurt – your dog may yelp when touched. Cancerous nodes? Usually painless until very large. Pain level shouldn't guide your concern though.

Can lymph node swelling in dogs be benign?

Absolutely. Studies show about 40% of swellings are non-cancerous. But guess what? You can't tell by feeling. Diagnostic testing is non-negotiable.

What's the survival rate for lymphoma in dogs?

With full chemo protocol, 85-90% achieve remission. Average survival is 12-14 months. Some dogs live 2+ years. But prognosis varies wildly by cancer type – your vet will explain specifics.

Can I check my dog's lymph nodes at home?

Please do! Run your hands along:

  • Under jawline
  • Shoulder fronts
  • Armpits
  • Groin creases
  • Behind knees

Do this monthly. Finding changes early is everything.

When to Truly Worry About Swollen Lymph Nodes in Dogs

Let's get brutally honest. Rush to the ER if you see:

  • Multiple swollen nodes at once
  • Rapid size increase (doubling in days)
  • Rock-hard texture
  • Weight loss or appetite loss with swelling
  • Difficulty breathing or swallowing

Notice swelling of lymph nodes in dogs combined with these? Don't wait until Monday.

Financial Reality Check: Paying for Care

Let's talk money because treatment costs blindside people:

Diagnostic/Treatment Low End Cost High End Cost Ways to Reduce
Initial Diagnosis $300 $800 Request itemized estimates
Lymphoma Chemotherapy $3,500 $8,000 Ask about payment plans
Steroid-Only Treatment $50/month $150/month Price shop pharmacies
Emergency Surgery $2,000 $5,000+ Pet insurance (get BEFORE diagnosis)

Pet insurance saved my neighbor $6k last year. Don't wait until you find lumps to enroll.

Final Thoughts From My Experience

Finding swollen lymph nodes on your dog is terrifying. Been there. But knowledge cuts the fear. Regular checks catch things early. Diagnostic testing? Non-negotiable. And treatment advances for lymphoma? Better than ever.

Remember that lump I mentioned at the start? Turned out to be a harmless reaction to a bee sting. But we only knew because we got it checked. So please – if you feel something unusual on your dog, pick up the phone.

How many times have you checked your dog's lymph nodes since starting this article? Exactly.

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